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| Synonym: | 1-[4-(1-Pyrrolidinyl)-2-butynyl]-2-pyrrolidinone |
| CAS Number: | 70-22-4 |
| Empirical Formula (Hill Notation): | C12H18N2O |
| Molecular Weight: | 206.28 |
| Beilstein Registry Number: | 1530948 |
| EC Number: | 200-728-0 |
| MDL number: | MFCD00003200 |
| O9126 Oxotremorine sesquifumarate salt ≥98% (HPLC), solid | O100 Oxotremorine M solid | C4382 Carbamoylcholine chloride ≥98% (titration), crystalline |
Description
| Biochem/physiol Actions | Muscarinic acetylcholine receptor agonist with preference for the M2 receptor. |
Properties
| assay | ≥95% (TLC) |
| form | liquid |
| color | clear, light yellow |
| refractive index | n20/D 1.517(lit.) |
| bp | 124 °C/0.1 mmHg(lit.) |
| solubility | H2O: soluble50 mg/mL |
| density | 1 g/mL at 25 °C(lit.) |
| storage temp. | 2-8°C |
Safety
References
| reference | Gupta, N., Muscarinic receptor M1 and M2 subtypes in the human eye: QNB, pirenzipine, oxotremorine, and AFDX-116 in vitro autoradiography. Br. J. Ophthalmol. 78, 555, (1994) |
| | Ringdahl, B., and Jenden, D.J., Pharmacological properties of oxotremorine and its analogs. Life Sci. 32, 2401, (1983) |
| | Puolivali, J., Oxotremorine suppresses thalamocortical oscillations via thalamic muscarinic acetylcholine receptors. Psychopharmacology 140, 285, (1998) |
| Merck | Merck 13,7020 |
| Beilstein | Beil. 21,V,6,370 |
| | Aldrich MSDS 1, 1416:D / Corp MSDS 1 (2), 2668:C / FT-IR 1 (2), 945:D / FT-IR 2 (3), 4042:B / FT-NMR 1 (3), 529:C / IR-Spectra (3), 1439:C / IR-Spectra (2), 1256:G / NMR-Reference 2 (2), 961:A / RegBook 1 (2), 2709:L / Sax 6, 2105 / Sigma FT-IR 1 (2), 816:B / Structure Index 1, 427:D:3 |
